Animal Health Care (AHC) segment feed materials are normally composed of plant material, cereals, and vegetable proteins. These cannot be fully digested and utilized. However, external addition of ingredients like feed supplements or enzymes to the feed increases them.

Many cereals have a proportion of their energy in the form of non-starch polysaccharides (NSPs), more commonly known as fiber. Enzymes will break down these NSPs which lead to increased metabolizable energy and protein utilization. In some cereals, a large part of the NSP is soluble and causes high viscosity in the intestine and improving feed utilization.

In order to address this important issue, Prathista invented “multizyme” a one in all product to improve feed quality. Multizyme is a very unique blend of enzymes produced by solid-state fermentation. It will take care of various problems in chickens like effect caused due to the presence of non-starch polysaccharides, galactosides, phytases, and other anti-nutritional factors present in the feedstuff.

The digestive system of chicken comprises of natural enzymes to digest complex molecules in the feed like proteins, carbohydrates, fats etc. Poultry feed involves many plant and animal origin ingredients.

  • Plant sources like corn, maize, wheat, oat, rye, bajra, rice, rice polish, millets like sorghum, bajra, dorb, soya bean meal, and sunflower cake etc.
  • Animal source includes fish meal, meat meal, liver meal, bone meal, and blood meal etc.

Animal residues are easily digestible by chicken; however, plant origin materials are not completely digestible due to the presence of certain inherent residues. These residues are not digested due to the lack of required endogenous enzymes. A customized blend of enzymes helps to unlock the valuable nutrients present in the inherent residues and thus, made bio-available to birds, which are not otherwise carried out.

These indigestible plant residues are

1) Non-starch polysaccharides
2) Galactosides
3) Phytases
4) Anti-nutritional components like lectins, tannins, trypsin inhibitor etc.


The term NSP covers a large class of polysaccharides excluding starch.

The term NSP covers a large class of polysaccharides excluding starch. NSP contents in some of the cereal grains are as below    

Feed Ingredients                    Total NSP (g/kg)
Sunflower cake                             367
Dorb                                             271
Soya meal                                     234
GNC                                              167
Maize                                            124
Jowar                                            99
Wheat                                           94
Rice Polish                                     87
Bajra                                             80


These are short-chain carbohydrates usually found in legumes like soybean. Galactose being the main subunit is cross-linked in raffinose, stachyose, and verbascose.


Any poultry feed generally contains phosphorus in organic forms as phytate phosphorus and non-phytate phosphorus. The non-phytate phosphorus is easily available and well digested by the chicken. However, it is found that phytate phosphorus is not available due to negligible amounts of phytase enzyme in the intestine of the bird not sufficient to hydrolyze the phytate bond. Due to this most of the organic phosphorus is passed undigested through feces causing environmental pollution.


ANFs like lectins, tannins, trypsin inhibitors etc. This class includes the chemically varied type of residues which usually occur in very low concentrations.

The undigested NSP’s will perform negative functions like

  • Increases gut viscosity thereby reducing digestion of feed
  • Modify gut physiology to reduce internal secretion of water, proteins, electrolytes, and lipids
  • Bind bile salts, lipids, and cholesterol thereby changing digestive and absorptive dynamics of the gut.
  • An increase retention time of digesta in the intestine thus decreasing oxygen tension to favor the growth of anaerobic toxigenic microflora causing deconjugation of bile

All these interactions lead to:
             i. Poor feed conversion
            ii. Loose droppings
           iii. Chronic deficiencies and other health-related problems in poultry.

Undigested galactosides interfere with the gut physiology leading to flatulence and poor assimilation of nutrients.

Undigested phytates chelate minerals like Ca, Fe, Mg, starch, and amino acids etc. making them biologically unavailable. Hence, there is an extra supplementation of inorganic phosphorus in the feed to maintain the mineral level in the bird which again increases the feed cost. 

Other ANF’s hampers digestion by interfering with the endogenous enzyme present in the digestive tract. Inhibit the action of trypsin, tannins, lectins etc.



  • Optimizes the use of conventional and non-conventional feed ingredients.
  • Improves feed conversion ratio (FCR)
  • Increase in weight gain of broilers, the number of eggs in layers
  • Reduces wet droppings, odor and improves litter quality (Less microbial contamination) leading to cleaner eggs.
  • Improves absorption efficiency of antibiotics, methionine, and lysine etc.


Application of enzymes in MULTIZYME
  • Alpha-amylase: hydrolyzes alpha-1, 4 glycosidic bonds from starchy material liberating metabolizable sugar.
  • Cellulase: hydrolyzes beta-1, 4-glycosidic bonds randomly from cellulosic fraction of soya, maize, dorb etc. To release easily metabolizable glucose.
  • Xylanase: hydrolyzes arabinoxylans in simple sugar.
  • Pectinase: hydrolyzes pectic acid in a random fashion from sfc and dorb to release metabolizable galacturonate sugars.
  • Phytase: hydrolyzes phytic acid to myo-inositol and phosphoric acid to reduce the anti-nutritional effect and release bio-available phosphorus, amino acids, and minerals.
  • Protease: acts on proteins to liberate peptides and amino acids.
  • Lipase: breakdown of the vegetable and animal fats to free fatty acids, triglycerides and glycerol to give metabolizable energy.
  • Hemi-cellulase acts on beta-1, 4 linked xylanopyranosyl residues of arabinoxylans and mannans releasing pentose sugars and metabolizable hexose sugars from sfc, wheat, dorb, causing the reduction in internal digesta viscosity.
  • Beta-galactosidase hydrolyzes galacto- oligosaccharides from soya like raffinose and stachyose into sucrose and galactose to reduce the anti-nutritional effect and release metabolizable sugars.
  • Glucanase decreases the viscosity of beta-glucans in high barley and wheat diets to release metabolizable sugars.

Besides, multiple enzymes, the “multizyme” is formulated with organic chelated micronutrients, vitamins and trace elements for better combination and multiple benefits.


"Multizyme" shelf-life is 24 months from the date of manufacturing under specified conditions


400 to 500 gms per ton of feed (or) as recommended by the nutritionist.


Multizyme is made available in 25 Kg HDPE packing or as per customer requirements.

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